Medical weight loss clinic in Charlotte, with in-person GLP-1 care
OneSpotMD is a physician-owned medical weight loss clinic in Charlotte, with locations in Steele Creek and Plaza Midwood. Our providers see you in person, check whether a GLP-1 medicine such as tirzepatide (Zepbound) or semaglutide (Wegovy) is right for you, and stay with you through every dose change. Insured patients are billed like any other visit, and we help with your medicine coverage. No insurance? Ask about our self-pay GLP-1 program. We’re open 7 days a week.
- ✓ In-person visits with a medical provider, not just an online form
- ✓ Tirzepatide (Zepbound, Mounjaro) and semaglutide (Wegovy, Ozempic) when they fit your health
- ✓ Insurance billed for visits, and help with your plan’s paperwork for your medicine
- ✓ No insurance? We can still see you, or you can join our self-pay GLP-1 program
- ✓ Program compounded injections are given at Steele Creek or Plaza Midwood; injectable pharmacy prescriptions are self-injected at home
- ✓ Open 7 days, weekdays until 8pm, with urgent care if side effects hit
Call either clinic to arrange your first weight loss visit. Insured patients are billed like any other visit, and we help with your medicine coverage. No insurance? Ask about our self-pay GLP-1 program.
What happens next: 1. Call either clinic. 2. Our team helps arrange your visit. 3. See a provider in person at Steele Creek or Plaza Midwood.
Cost: no insurance? Visits and labs are $99 a month. If individually prescribed and permitted, self-pay compounded tirzepatide is $199 or $299 a month, depending on your dose. With insurance, visits and labs are billed to your plan; your cost depends on your coverage. See what you’d pay
Never tried a GLP-1? Call a clinic to book a visit, and ask whether we have a sample you can try at your first appointment, before you sign up for the full program. Call to ask about a sample
On this page
How it worksMedicinesWho qualifiesResultsOther benefitsWhy in personSide effectsMore answersCost and insuranceOur clinics
How medical weight loss works at OneSpotMD
| Step | What happens |
|---|---|
| 1. Call a clinic | Call either clinic to arrange your visit. Be ready to discuss your health, weight history, medicines and insurance with our team. |
| 2. First visit | A provider reviews your history and medicines, checks your weight, BMI and blood pressure, and orders labs if you need them. You talk about your goals and what has and hasn’t worked before. |
| 3. Your plan | If a medicine fits, your provider picks the one that suits your health and your coverage, and gives you a simple plan for food, protein and activity. See GLP-1 medications. |
| 4. Getting your medicine | If your plan covers it, we send your prescription to your pharmacy and help with any prior approval your plan asks for. No coverage? Your provider goes over your options. See insurance coverage. |
| 5. Dose steps and check-ins | GLP-1 medicines start at a low dose that goes up slowly, usually about every 4 weeks, so your body can adjust. Your provider checks your progress and side effects before each step. See what to expect. |
| 6. Keeping it off | Once you reach a steady dose, we help you plan for the long term. See keeping weight off and stopping. |
Call to start weight loss care
GLP-1 weight loss medicines we prescribe
GLP-1 medicines lower your appetite and help you feel full sooner. Your provider decides with you which one fits, based on your health, your other medicines and what your insurance covers.
Tirzepatide is the main medicine we prescribe for weight loss. Some GLP-1 medicines now also come as a daily pill. Ask your provider which options fit you.
Who qualifies for weight loss medicine
The FDA approved Zepbound and Wegovy for adults with:
- A BMI of 30 or higher, or
- A BMI of 27 or higher plus at least one weight-related health problem, such as high blood pressure, type 2 diabetes or high cholesterol
Source: FDA: FDA approves new medication for chronic weight management (Nov 2023)
Your provider also checks for reasons a GLP-1 isn’t safe for you, such as a personal or family history of medullary thyroid cancer or MEN 2, or being pregnant or planning a pregnancy. Not sure about your BMI? See who qualifies and a BMI chart.
How much weight people lose
Results vary from person to person. In the large studies that led to FDA approval, people took the medicine along with a lower-calorie diet and more activity:
| Study | Medicine | Average weight loss |
|---|---|---|
| SURMOUNT-1 (72 weeks) | Tirzepatide 5, 10 or 15 mg weekly | 15.0%, 19.5% and 20.9% of body weight, vs 3.1% with placebo |
| STEP 1 (68 weeks) | Semaglutide 2.4 mg weekly | 14.9% of body weight, vs 2.4% with placebo |
Source: Jastreboff AM, et al. Tirzepatide once weekly for the treatment of obesity (SURMOUNT-1). NEJM 2022; Wilding JPH, et al. Once-weekly semaglutide in adults with overweight or obesity (STEP 1). NEJM 2021
Most weight loss happens slowly over months, not weeks. Weight often comes back if the medicine is stopped, which is why we plan for the long term from the start. See keeping weight off and stopping.
What else weight loss can help with
Losing even part of your extra weight can improve more than the number on the scale. Here’s what research and FDA approvals show. Results vary, and your provider tracks what changes for you.
- Blood pressure, cholesterol and blood sugar: even modest weight loss can help improve all three.
- Type 2 diabetes: Mounjaro and Ozempic are FDA-approved to lower blood sugar in adults with type 2 diabetes. In people with prediabetes, a large NIH study found that losing about 7% of body weight through diet and exercise lowered the chance of getting type 2 diabetes by 58%.
- Sleep apnea: Zepbound is FDA-approved to treat moderate to severe obstructive sleep apnea in adults with obesity.
- Heart health: in adults with heart disease and overweight or obesity, Wegovy lowered the risk of heart attack, stroke and death from heart disease.
- Fatty liver (MASH): Wegovy injection has accelerated FDA approval for adults with noncirrhotic MASH and moderate-to-advanced liver scarring (F2–F3). This is not an approval for every type of fatty liver disease or for Wegovy tablets.
- PCOS: losing weight can ease many PCOS symptoms and can help make periods more regular. GLP-1 medicines are not FDA-approved to treat PCOS, so your provider decides with you whether one fits.
- Knee and joint pain: in one study, each pound lost took about 4 pounds of pressure off the knees. In a 68-week trial of adults with obesity and knee arthritis, people taking semaglutide had less knee pain than people taking a placebo. Some people also notice less back pain as they lose weight, though there’s less research on that.
Source: CDC: Losing weight; Mounjaro prescribing information, Eli Lilly (rev. 8/2026); NIDDK (NIH): Diabetes Prevention Program; FDA: FDA approves first medication for obstructive sleep apnea (Dec 2024); Lincoff AM, et al. Semaglutide and cardiovascular outcomes in obesity without diabetes (SELECT). NEJM 2023; AACE: FDA approves Wegovy for certain adults with MASH (Aug 2025); NICHD (NIH): Treatments for PCOS; Arthritis Foundation: Weight loss benefits for arthritis; Once-weekly semaglutide in persons with obesity and knee osteoarthritis (STEP 9), NEJM 2024
Each GLP-1 medicine is approved for specific uses. Your provider explains which ones apply to the medicine you take.
Why local, in-person weight loss care
| OneSpotMD | Online-only programs | |
|---|---|---|
| See a provider in person | Yes, at either clinic | Usually video or forms only |
| Blood pressure, diabetes and cholesterol care | Yes, with our primary care team | Usually not |
| Labs and EKG | Drawn and done in our clinics | Sent to an outside lab, if at all |
| Help with side effects | Walk in 7 days a week, weekdays until 8pm | Often told to see your own doctor or urgent care |
| Insurance for visits | Billed to your plan | Often cash only |
| Weekly compounded-program injections in clinic | Available at both clinics | Not available |
Already on a GLP-1 through an online program? We can take over your care in person. See switching to in-person care.
Call to start weight loss care
Side effects and safety
The most common side effects are nausea, diarrhea, vomiting and constipation. They are usually mild to moderate and show up most often when your dose goes up. Your provider helps you manage them, and if they get bad, you can walk in to either clinic. See side effects.
- Severe stomach pain that won’t go away, with or without vomiting. It may spread to your back.
- Signs of a serious allergic reaction: swelling of your face, lips, tongue or throat, trouble breathing or swallowing, or a fast heartbeat with dizziness
- Fainting, or chest pain
- Anything that seems life-threatening
- Sudden loss of vision: seek emergency medical care immediately.
Come in to either clinic the same day for:
- Nausea, vomiting or diarrhea that keeps you from drinking enough fluids
- Signs of dehydration: dizziness, very dark urine or peeing much less than usual
- No bowel movement for several days, with belly pain or bloating
- Pain in your upper right belly, fever, or yellowing of your skin or eyes (possible gallbladder problem)
- A lump or swelling in your neck, trouble swallowing, or hoarseness that won’t go away
Source: Zepbound prescribing information, Eli Lilly (rev. 8/2026); Wegovy prescribing information, FDA (rev. 5/2026)
Answers to your other questions
Cost and insurance
What you pay each month
Your visits and your medicine are priced separately, so you only pay for what your insurance doesn’t cover.
| Your situation | Visits and labs | Medicine | Each month |
|---|---|---|---|
| Self-pay program, individually prescribed compounded dose 2.5–7.5 mg | $99 | $199 | $298 |
| Self-pay program, individually prescribed compounded dose 10–15 mg | $99 | $299 | $398 |
| Insurance covers your medicine | Your plan-dependent cost | Your plan-dependent pharmacy cost | Your plan-dependent cost |
| Insurance does not cover medicine; compounded treatment individually prescribed if appropriate | Your plan-dependent cost | $199 or $299 | Your plan-dependent visit/lab cost plus eligible prescribed medicine |
- $99 a month, no insurance needed: a visit with your provider every month and lab work every 3 months. Self-pay patients can sign up for this program.
- With insurance: we bill your plan for your visits and labs. Your cost depends on your plan, including copay, coinsurance and deductible.
- If your plan covers tirzepatide (Zepbound or Mounjaro): we send your prescription to your pharmacy, and your out-of-pocket cost depends on your plan. Many plans need prior approval first, and we help with the paperwork.
- If prescribed for your individual medical need: compounded tirzepatide is $199 a month at 2.5, 5 or 7.5 mg, or $299 a month at 10, 12.5 or 15 mg. Compounded medicine is considered only when an individual medical need cannot be met by an FDA-approved drug and applicable requirements permit it. Cost or lack of insurance coverage alone does not determine eligibility. Your provider determines your dose and follow-up plan.
Compounded tirzepatide is not FDA-approved. The FDA does not review compounded medicines for safety, effectiveness or quality. Your provider talks with you about whether it’s right for you. Prices as of November 2026. HSA and FSA cards are accepted. Compounded medicine is considered only when an individual medical need cannot be met by an FDA-approved drug and applicable requirements permit it. Cost or lack of insurance coverage alone does not determine eligibility.
How insurance coverage for GLP-1 medicine works →
Insurance we take: Blue Cross Blue Shield PPO plans, Aetna, Cigna, UnitedHealthcare, Humana and TRICARE East, plus Original Medicare and most Medicare Advantage plans. We don’t take HMO plans tied to one doctor or hospital system. HSA and FSA cards are accepted. See all the insurance we accept.
Our weight loss clinics in Charlotte
Injectable prescriptions sent to a pharmacy are self-injected at home as instructed. Oral medicines are taken as prescribed. Patients prescribed compounded medicine through our program receive weekly injections at the clinic. A routine provider evaluation is not required at every weekly injection; follow-up and dose changes remain directed by your provider.
| Clinic | Address and phone |
|---|---|
| Steele Creek | 2114 Freeman Park Dr, Suite 105, Charlotte, NC 28273. (980) 880-5588 |
| Plaza Midwood | 2017 Central Ave, Suite 103, Charlotte, NC 28205. (704) 731-8656 |
| Hours (both) | Monday to Friday 8am to 8pm; Saturday and Sunday 9am to 5pm |
Weight loss visits and in-clinic injections are available at both clinics. Close to Steele Creek, Ballantyne, Rivergate, Lake Wylie, Fort Mill, Plaza Midwood, NoDa, Uptown, Midtown and Elizabeth.
Call either clinic to discuss weight loss care and arrange your first visit.
Frequently asked questions
What is medical weight loss?
Medical weight loss is a weight loss program run by a medical provider. It can include prescription medicine such as a GLP-1, along with a plan for food, activity and follow-up visits. At OneSpotMD, a provider sees you in person at one of our two Charlotte clinics.
Do you offer weight loss injections in Charlotte?
Yes. Providers prescribe medicine when appropriate after an evaluation. Zepbound and Wegovy have weight-management indications; Ozempic and Mounjaro are diabetes medicines, and prescribing them specifically for weight loss is off-label. Injectable prescriptions sent to a pharmacy are self-injected at home as instructed. Oral medicines are taken as prescribed. Patients prescribed compounded medicine through our program receive weekly injections at the clinic. A routine provider evaluation is not required at every weekly injection; follow-up and dose changes remain directed by your provider. Compounded medicine is considered only when an individual medical need cannot be met by an FDA-approved drug and applicable requirements permit it. Cost or lack of insurance coverage alone does not determine eligibility.
Which weight loss medicines do you prescribe?
Our providers prescribe GLP-1 medicines including tirzepatide (Zepbound and Mounjaro) and semaglutide (Wegovy and Ozempic). Tirzepatide is the main one we use for weight loss. Your provider picks the medicine that fits your health and what your insurance covers.
Who qualifies for weight loss medication?
The FDA approved Zepbound and Wegovy for adults with a BMI of 30 or higher, or 27 or higher with at least one weight-related condition such as high blood pressure, type 2 diabetes or high cholesterol. Your provider also checks for reasons a GLP-1 might not be safe for you.
Do you take insurance for weight loss care?
Yes. We bill your insurance for your visits, including Blue Cross Blue Shield PPO plans, Aetna, Cigna, UnitedHealthcare, Humana, TRICARE East and Medicare. Coverage for the medicine itself depends on your plan, and many plans need prior approval first.
Does insurance cover Zepbound or Wegovy?
It depends on your plan. Some plans cover them with prior approval, and some don’t cover weight loss medicine at all. We help with the paperwork your plan asks for, and your provider goes over your options if your plan says no.
What if I don’t have insurance?
We can still see you. You can be seen as a self-pay patient, or join our self-pay GLP-1 program. Your provider talks with you about your options at your visit.
Do you offer compounded semaglutide or tirzepatide?
Your provider can discuss the options for your individual medical needs. Compounded medicine is considered only when an individual medical need cannot be met by an FDA-approved drug and applicable requirements permit it. Cost or lack of insurance coverage alone does not determine eligibility. Compounded medicines are not FDA-approved. FDA does not review them for safety, effectiveness or quality.
How much weight can I lose on a GLP-1?
Results vary. In the SURMOUNT-1 study, adults on tirzepatide lost an average of 15% to 21% of their body weight over 72 weeks, depending on the dose. In the STEP 1 study, adults on semaglutide 2.4 mg lost an average of about 15% over 68 weeks. Both studies included diet and activity changes.
How fast will I lose weight?
Slowly at first. GLP-1 medicines start at a low dose that goes up about every 4 weeks, so most people see steady loss over several months rather than right away. Your provider tracks your progress at each check-in.
Do I have to come in person?
Yes, your care starts with an in-person visit, so your provider can check your weight, blood pressure and health history and order labs if you need them. Follow-ups can be at either of our Charlotte clinics, 7 days a week.
Can I get my weekly shot at the clinic?
Injectable prescriptions sent to a pharmacy are self-injected at home as instructed. Oral medicines are taken as prescribed. Patients prescribed compounded medicine through our program receive weekly injections at the clinic. A routine provider evaluation is not required at every weekly injection; follow-up and dose changes remain directed by your provider. Compounded medicine is considered only when an individual medical need cannot be met by an FDA-approved drug and applicable requirements permit it. Cost or lack of insurance coverage alone does not determine eligibility.
What are the side effects of GLP-1 medicines?
The most common are nausea, diarrhea, vomiting and constipation, usually mild to moderate and most common when your dose goes up. Call 911 for severe stomach pain that won’t go away, signs of a serious allergic reaction, or anything that seems life-threatening.
What happens if I stop the medicine?
Many people regain weight after stopping. In the SURMOUNT-4 study, people who switched from tirzepatide to placebo regained much of the weight they had lost. Talk with your provider before stopping, and we’ll plan the next step together.
Can I take a GLP-1 if I have type 2 diabetes?
Often, yes. Mounjaro and Ozempic are approved for type 2 diabetes, and Zepbound and Wegovy for weight loss. Our primary care team can manage your diabetes and your weight together.
Do you treat teenagers for weight loss?
Our weight loss program is for adults. Teens should see their pediatrician about weight management.
How do I get started?
Call either clinic to arrange a visit. Our team helps arrange your first visit at Steele Creek or Plaza Midwood.
How much does medical weight loss cost at OneSpotMD?
Self-pay patients can join the $99-a-month visit and lab program, with a monthly provider visit and labs every 3 months. If compounded tirzepatide is individually prescribed and permitted, medicine costs $199 a month at 2.5, 5 or 7.5 mg, or $299 a month at 10, 12.5 or 15 mg: $298 or $398 including the program. We bill your insurance for visits and labs. What you pay depends on your plan, including any copay, coinsurance and deductible. Pharmacy prescription costs also depend on your coverage. Compounded medicine is considered only when an individual medical need cannot be met by an FDA-approved drug and applicable requirements permit it. Cost or lack of insurance coverage alone does not determine eligibility. Compounded tirzepatide is not FDA-approved; FDA does not review it for safety, effectiveness or quality.
Can losing weight help my blood pressure, diabetes or joint pain?
It can. Even modest weight loss can help improve blood pressure, cholesterol and blood sugar, and losing weight takes pressure off your knees. Some GLP-1 medicines are also FDA-approved for other uses: Zepbound for obstructive sleep apnea in adults with obesity, and Wegovy to lower heart risk in adults with heart disease and Wegovy injection has accelerated approval for noncirrhotic MASH with moderate-to-advanced liver scarring (F2–F3) in adults. Results vary, and your provider tracks what changes for you.
Can I try a sample before I sign up for the full program?
Often, yes. We usually have samples in the clinic. Call either clinic to book a visit and ask whether one is available. If your provider decides a GLP-1 medicine is right for you, you may be able to try a sample at your first appointment before you sign up for the full program. Samples depend on what we have in stock.
Sources
Additional safety information: FDA: compounded GLP-1 medicines; FDA: November 2026 vision warning; Wegovy prescribing information.
- FDA: FDA approves new medication for chronic weight management (Nov 2023)
- CDC: Adult BMI categories
- Jastreboff AM, et al. Tirzepatide once weekly for the treatment of obesity (SURMOUNT-1). NEJM 2022
- Wilding JPH, et al. Once-weekly semaglutide in adults with overweight or obesity (STEP 1). NEJM 2021
- Aronne LJ, et al. Continued treatment with tirzepatide for maintenance of weight reduction (SURMOUNT-4). JAMA 2024
- Zepbound prescribing information, Eli Lilly (rev. 8/2026)
- Wegovy prescribing information, FDA (rev. 5/2026)
- FDA: Concerns with unapproved GLP-1 drugs used for weight loss
- NIDDK (NIH): Prescription medications to treat overweight and obesity
- CDC: Losing weight
- Mounjaro prescribing information, Eli Lilly (rev. 8/2026)
- NIDDK (NIH): Diabetes Prevention Program
- FDA: FDA approves first medication for obstructive sleep apnea (Dec 2024)
- Lincoff AM, et al. Semaglutide and cardiovascular outcomes in obesity without diabetes (SELECT). NEJM 2023
- AACE: FDA approves Wegovy for certain adults with MASH (Aug 2025)
- NICHD (NIH): Treatments for PCOS
- Arthritis Foundation: Weight loss benefits for arthritis
- Once-weekly semaglutide in persons with obesity and knee osteoarthritis (STEP 9), NEJM 2024
This page is general information, not medical advice for your situation. Your provider decides with you whether a medicine is right for you. Results vary from person to person.
Ozempic® and Wegovy® are registered trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are registered trademarks of Eli Lilly and Company. OneSpotMD is not affiliated with or endorsed by these companies.
More on medical weight loss
Medicines
GLP-1 medicinesTirzepatideZepboundMounjaroSemaglutideWegovyOzempicGLP-1s compared
Before you start
Getting startedInsurance coverage
Once you start
Side effectsDiet, exercise and keeping it off
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